Invasive fungal rhino sinusitis and Diabetes
Whenever as a doctor you get a patient with some serious illness which is difficult to manage, a sense of gloominess prevails. Patients of uncontrolled diabetes do get some life threatening infections and to treat them becomes a challenge. Invasive fungal rhino sinusitis is one such dreaded infection which until recently was having almost fatal outcome and even if saved were left with serious morbidities like lost vision, lost orbit. The only effective anti fungal amphotericine is highly toxic and its liposomal variant is expensive. Last month managed one such pt, a 50 yr old lady with uncontrolled diabetes , blood sugar levels touching 350 mg/dl admitted in the hospital with severe headache, diplopia due to ophthalmoplegia of rt eye. Diagnostic nasal endoscopy revealed pale darkening mucosa , took smear and tissue for biopsy. CT and MRI revealed opacities in adjoining ethmoid and frontal sinuses. All the picture was suggestive o...